Case Study – Advanced PDR with Non-Perfusion and Macular Edema

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33-year-old Caucasian female with history of myopia, vulvar cancer, family history of diabetes and liver cancer presented with a visual acuity of 20/200 (OD), 20/50 (OS). Intraocular pressures were measured 17mmHg (OD), 19mmHg (OS). A posterior subcapsular cataract was observed with all other ocular physiological characteristics normal.

3D Wide OCT Combination Scans, fluorescein angiography and fundus photos were obtained OU. Macular edema, subretinal fluid, intraretinal hemorrhages, cotton wool spots (CWS), nonperfusionable vessels and hemorrhages in the peripheral vessels were visualized OU.

Diagnosis: Advanced Proliferative Diabetic Retinopathy (PDR), retinal non-perfusion and macular edema OU

Treatment: Bevacizumab, PRP laser (OU)

Discussion: 45-degree fluorescein images, true-color photos of the retina and penetrating swept-source OCT scans helped to confirm and document the clinical findings

Figure 1: Color Fundus Photo (OU)
Figure 2: Red-free Fundus Photo (OU)
Figure 3: 3D Wide Combination Scan (OD)
Figure 4: 3D Wide Combination Scan (OS)
Figure 5: Early Phase Fluorescein Angiogram (OU)
Figure 6: Peripheral Fluorescein Angiogram Superotemporal (OD), Nasal (OS)
Figure 7: Late Phase Fluorescein Angiogram (OU)

Captured with

Topcon DRI Triton Swept-Source OCT Fundus Camera (October 2022)

Case and Images Courtesy of

Jonathan Barofsky, MD, FACS
Retina Care Center Lakewood, NJ USA

*The opinions, ideas, views and assumptions expressed are the author’s own and do not
necessarily represent the views of Topcon, nor do they constitute advice from Topcon.

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